A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/159, 167/310
A61K 47/18 (2006.01)
Patent
CA 1176167
ABSTRACT OF THE DISCLOSURE Greatly enhanced delivery of a wide variety of bio-affecting agents is provided by fomulations for topical application comprising at least one bio- affecting agent and N,N-diethyl-m-toluamide, optionally further comprising a non-toxic topical carrier. N,N- Diethyl-m-toluamide (DEET) acts as a uniquie transmport agent which delivers the active agent across the stratum corneum to the targen area. Cosmetic and therapeutic dermatological agents as well as systemically effective therapeutic agents can be formulated with DEET and effectively delivered through the skin to the desired site, i.e. to the underlying tissues of the epidermis and sermis or to the general circulation.
371672
Caldwell Larry J.
Haslam John L.
Windheuser John J.
Goudreau Gage Dubuc
Merck & Co. Inc.
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