Use of n-phenyl-2-pyrimidineamine derivatives against mast...

A - Human Necessities – 61 – K

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A61K 31/506 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2443092

Use of the N-phenyl-2-pyrimidine-amine derivatives of formula I, in which the symbols and substituents have the meaning as given herein in free form or in pharmaceutically acceptable salt form in the manufacture of a pharmaceutical composition for the treatment of allergic rhinitis, allergic dermatitis, drug allergy or food allergy, angioedema, urticaria, sudden infant death syndrome, bronchopulmonary aspergillosis, multiple sclerosis or mastocytosis.

L'invention concerne l'utilisation de dérivés de N-phényl-2-pyrimidine-amine de formule I, dans lesquels les symboles et les substituants ont la signification ci-après sous une forme libre ou sous la forme d'un sel acceptable pharmaceutiquement. On utilise ces dérivés dans la production d'une composition pharmaceutique destinée au traitement de la rhinite allergique, de la dermite allergique, d'une allergie aux médicaments ou d'une allergie alimentaire, d'un oedème de Quincke, de l'urticaire, du syndrome de mort subite du nourrisson, de l'aspergillose broncho-pulmonaire, de la sclérose en plaques ou de la mastocytose.

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