A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 9/51 (2006.01) A61K 31/12 (2006.01) A61K 31/575 (2006.01) A61K 31/765 (2006.01) A61K 47/28 (2006.01) A61K 31/71 (1995.01)
Patent
CA 2103447
The invention refers to the use of an inert, structure-giving, deadjuvanated matrix of a complex of a sterol, such as cholesterol, and one or more saponins as a carrier for the administration at of a pharmaceutically active substance, and a drug carrying particle comprising said inert structure-giving matrix to which has been connected a pharmaceutically active substance. The drug carrying particle, delpha, has an annular basic structure which can form spherical nano particles having a size of 30-50 nm and a narrow size distribution.
Utilisation d'une matrice inerte, exempte d'adjuvant, et conférant une structure, d'un complexe formé un stérol, tel que le cholestérol, et d'une ou plusieurs saponines, en tant qu'excipient destiné à l'administration d'une substance pharmaceutiquement active et particule porteuse d'un médicament comprenant ladite matrice inerte et conférant une structure, à laquelle on a lié une substance pharmaceutiquement active. Ladite particule porteuse de médicament, delpha, présente une structure de base annulaire qui peut former des nanoparticules sphériques ayant une taille de 30 à 50 nm et une répartition granulométrique étroite.
Lovgren Karin
Morein Bror
Fetherstonhaugh & Co.
Iscovent Ab
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