Use of nitric oxide in the treatment of exercised induced...

A - Human Necessities – 61 – M

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A61M 15/00 (2006.01) A61M 16/00 (2006.01) A61M 16/10 (2006.01)

Patent

CA 2226409

The administration of nitric a oxide in controlled doses to horses during high intensity exercise is described. The nitric oxide is beneficial to prevent exercise induced pulmonary hemorrhaging by reducing pulmonary artery pressure with concomitant compensating reduction in pulmonary vascular resistance. The nitric oxide is either administered to the equine through inhalation during exercise or via a stand alone nitric oxide gas source (12) followed by an intramuscular injection of nitric oxide augmenter prior to exercise.

L'invention concerne l'administration d'oxyde nitrique à des doses déterminées à des chevaux pendant un entraînement très intense. L'oxyde nitrique présente l'avantage de prévenir l'hémorragie pulmonaire due à l'entraînement par la réduction de la pression artérielle pulmonaire avec une réduction compensatrice concommittente de la résistance vasculaire pulmonaire. L'oxyde nitrique est administré au cheval soit par inhalation pendant l'entraînement soit par l'intermédiaire d'une source (12) d'oxyde nitrique gazeux autonome suivie d'une injection intramusculaire d'un augmenteur d'acide nitrique avant l'entraînement.

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