A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/198 (2006.01) A61P 29/00 (2006.01) A61P 39/06 (2006.01)
Patent
CA 2189762
Use of a NO scavenger or an inhibitor or antagonist for the production of a pharmaceutical composition for the treatment of migraine or other vascular headaches is described, as well as a method for the treatment of migraine or other vascular headaches in mammals, which comprises administering to said mammal an effective amount for said treatment of a NO scavenger or a specific inhibitor or antagonist. The active principle is desirably a NO synthase inhibitor, preferably L-NMMA.
L'invention concerne l'utilisation d'un capteur ou d'un inhibiteur ou d'un antagoniste d'oxyde nitrique dans la production d'une composition pharmaceutique destinée à traiter la migraine ou d'autres maux de tête vasculaires ainsi qu'un procédé de traitement de la migraine ou d'autres maux de tête vasculaires chez les mammifères. L'invention comprend l'administration audit mammifère d'une quantité efficace d'un capteur d'oxyde nitrique ou d'un inhibiteur ou d'un antagoniste spécifique. Le principe actif est idéalement un inhibiteur de synthase de l'oxyde nitrique, de préférence la L-NG-monométhylarginine.
Aps Kbus 17 Nr. 1797
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Olesen Jes
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