Use of nonviable particles comprising an internal control...

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) A61K 9/127 (2006.01)

Patent

CA 2420845

The present invention relates to the use of non-viable particles (and in particular liposome particles, particles which are in the form of a viral protein coat, non-viable genetically modified organisms or particles made of synthetic polymers), comprising an internal control (IC) nucleic acid sequence as an internal control in nucleic acid-based analysis. The present invention further relates to non-viable particles comprising an IC nucleic acid and kits for carrying out the methods and uses of the invention.

La présente invention concerne l'utilisation de particules non-viables (et en particulier de particules de liposomes, de particules sous forme de capside virale, d'organismes génétiquement modifiés non-viables ou de particules faites de polymères synthétiques), comportant une séquence d'acide nucléique témoin interne servant de témoin interne dans l'analyse par acide nucléique. La présente invention concerne encore des particules non-viables comportant un acide nucléique témoin interne et des trousses pour la mise en oeuvre des procédés et des utilisations selon l'invention.

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