Use of nucloeoside derivatives comprising a citrate group...

Details Use of nucloeoside derivatives comprising a citrate group... Use of nucloeoside derivatives comprising a citrate group...

G - Physics

01

N

G01N 33/531 (2006.01) C07H 19/02 (2006.01) C07K 16/44 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2478122

The invention concerns the use of nucleoside analogues comprising a citrate group for obtaining immunogens designed for producing antibodies having an affinity for triphosphorylated nucleosides. The invention also concerns the uses of said resulting antibodies for implementing sensitive immunologic methods of assaying said triphosphorylated nucleoside derivatives.

La présente invention concerne l'utilisation d'analogues de nucléosides comportant un groupement citrate pour l'obtention d'immunogènes aptes pour la production d'anticorps ayant une affinité pour des nucléosides triphosphorylées. Elle concerne également les applications des anticorps ainsi obtenus pour la mise en oeuvre des méthodes immunologiques sensibles de dosage desdits dérivés nucléosidiques triphosphorylés.

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