Use of p97 as an enzyme delivery system for the delivery of...

Details Use of p97 as an enzyme delivery system for the delivery of... Use of p97 as an enzyme delivery system for the delivery of...

C - Chemistry, Metallurgy

07

K

C07K 19/00 (2006.01) A61K 38/40 (2006.01) A61K 38/47 (2006.01) A61K 47/48 (2006.01) A61P 3/00 (2006.01) C12N 9/24 (2006.01) C12N 9/96 (2006.01) C12Q 1/02 (2006.01) G01N 33/50 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2472937

The present invention provides for compositions and methods for treating, ameliorating or preventing a lysosomal storage disease by administering to a patient suffering from a lysosomal storage disease a P97 conjugated with an enzyme which is capable of transportation into the lysosomes of cells on either sides of the blood brain barrier.

L'invention concerne des compositions et des procédés destinés à traiter, à améliorer ou à prévenir une maladie lysosomale par administration à un patient souffrant de cette maladie d'un p97 conjugué avec une enzyme capable de transporter des cellules dans les lysosomes de chaque côté de la barrière hémato-encéphalique.

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