Use of pactimibe for the preparation of a drug intended to...

A - Human Necessities – 61 – K

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Details

A61K 31/405 (2006.01) A61K 31/404 (2006.01) A61P 17/08 (2006.01) A61P 17/10 (2006.01)

Patent

CA 2692842

The invention relates to the use of at least one compound selected from among N-(1-octyl-5-carboxymethyl-4,6-dimethylindolin-7-yl)-2,2-dimethylpropanamide (pactimibe) having formula (I), the pharmaceutically acceptable salts thereof and the pharmaceutically acceptable solvates of same, for the preparation of a drug intended to prevent or treat a disorder caused by a sebaceous gland dysfunction in humans or animals, such as acne and/or any condition or disorder linked to an overproduction of sebum, for example seborrheic dermatitis, oily skin or oily scalp.

La présente invention a pour objet l'utilisation d'au moins un composé choisi parmi la N-(1-octyl-5-carboxyméthyl-4, 6-diméthylindolin-7-yl)-2,2-diméthylpropanamide (pactimibe) de formule (I) ses sels pharmaceutiquement acceptables et ses solvates pharmaceutiquement acceptables, pour la préparation d'un médicament destiné à prévenir ou à traiter un désordre dû à un dysfonctionnement des glandes sébacées chez l'homme ou l'animal comme par exemple l'acné et/ou tout état ou pathologie lié à une surproduction de sébum, comme par exemple la dermite séborrhéique, la peau grasse ou le cuir chevelu gras.

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