Use of paliperidone for the treatment of sleep disturbances...

Details Use of paliperidone for the treatment of sleep disturbances... Use of paliperidone for the treatment of sleep disturbances...

A - Human Necessities

61

K

A61K 31/519 (2006.01)

Patent

CA 2558704

The present invention provides a pharmaceutical composition, and provides for the use thereof for the treatment of excessive daytime sleepiness and/or a sleep disturbance in a psychiatric patient is need thereof. The pharmaceutical composition comprises a therapeutically effective amount of paliperidone, its pharmaceutically acceptable acid addition salts, enantiomeric forms, or esters thereof, together with a pharmaceutical carrier, and provides a relatively low plasma, concentration variation of paliperidone to the psychiatric patient in need of treatment. The present invention also provides for the use of a pharmaceutical composition as defined above for improving symptoms of schizophrenia in a psychiatric patient in need thereof, wherein the symptoms are selected from the group consisting of sleep disturbances and excessive daytime sleepiness.

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