Use of particles of a biocompatible, bioabsorbable calcium...

A - Human Necessities – 61 – K

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A61K 33/10 (2006.01) A61K 31/19 (2006.01) A61K 31/191 (2006.01) A61K 31/194 (2006.01) A61K 31/66 (2006.01) A61K 33/06 (2006.01) A61K 33/42 (2006.01) A61L 27/00 (2006.01) A61L 27/02 (2006.01) A61L 27/12 (2006.01) A61L 27/22 (2006.01) A61L 27/36 (2006.01) A61L 27/38 (2006.01) A61L 27/58 (2006.01) C12N 5/00 (2006.01) A61F 2/00 (2006.01)

Patent

CA 2139865

Use of at least one biocompatible, bioabsorbable calcium salt in the form of particles smaller than 8 mm as active principle in the preparation of a medicament for local treatment of bone deminerilizing diseases or bone mineralization disorders by implantation thereof in the spongy portion or medullary canal of the bone, particularly for restarting the process of bone remineralization and reconstruction of the absorbed trabeculae of bone. In patients suffering from osteoporosis, for example, this treatment shows reinitialization of the remineralization process and reconstruction of the trabeculae of bone, with a considerable increase in the bone stock of the bone treated.

Utilisation d'au moins un sel calcium biocompatible et biorésorbable, sous forme de particules, ayant des dimensions inférieures à 8 mm, comme ingrédients actif dans la préparation d'un médicaments destiné au traitement local, par implantation dans la partie spongieuse ou le canal médullaire de l'os, des maladies liées à la déminéralisation ou à des troubles de minéralisation de l'os, en particulier dans le but de relancer le processus de reminéralisation de l'os et de reconstruction des travées osseuses résorbées. Par l'exemple, chez les maladies atteints d'ostéoporose, ce traitement permet d'observer une relance du processus de reminéralisation et la reconstruction des travées osseuses, avec une augmentation très importante de la masse osseuse de l'os traité.

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