Use of pde iii inhibitors or calcium sensitizers for the...

Details Use of pde iii inhibitors or calcium sensitizers for the... Use of pde iii inhibitors or calcium sensitizers for the...

A - Human Necessities

61

K

A61K 31/4166 (2006.01) A61K 31/4439 (2006.01) A61K 31/444 (2006.01) A61K 31/50 (2006.01) A61K 31/501 (2006.01) A61P 9/04 (2006.01)

Patent

CA 2629367

The invention relates to use of a phosphodiesterase type III (PDE . Ill) inhibitor or Ca 2+- sensitizing agent or a pharmaceutically acceptable derivative thereof for preparation of a medication for the prolongation of time until onset of clinical symptoms in patients having an asymptomatic (occult) heart failure or for the reduction of heart size of a patient, suffering from asymptomatic (occult) heart failure.

La présente invention concerne l'utilisation d'un inhibiteur de la phosphodiestérase de type III (PDE III) ou d'un agent sensibilisant au Ca2 +-, ou d'un de leurs dérivés pharmaceutiquement acceptables, pour la préparation d'un médicament permettant de prolonger la durée qui précède l'apparition de symptômes cliniques ou de réduire la taille du cAEur chez des patients ayant une insuffisance cardiaque asymptomatique (occulte).

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