Use of pde1c and inhibitors thereof

Details Use of pde1c and inhibitors thereof Use of pde1c and inhibitors thereof

A - Human Necessities

61

K

A61K 31/00 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2611386

The present invention relates to the use of PDE1C as a novel target for the identification of compounds, which can be used for the treatment of pulmonary hypertension, fibrotic lung diseases or other fibrotic diseases outside the lung. The present invention further relates to the use of PDE1 C inhibitors in the manufacture of pharmaceutical compositions for use in the therapy of those diseases.

La présente invention concerne l'utilisation de PDE1C comme nouvelle cible pour l'identification de composés, qui peut être utilisé pour le traitement de l'hypertension pulmonaire, des pneumopathies fibrosantes et d'autres maladies fibrosantes hors des poumons. Cette invention concerne aussi l'utilisation d'inhibiteurs de PDE1 C dans la fabrication de compositions pharmaceutiques destinées à la thérapie de ces maladies.

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