Use of peptide-drug conjugation to reduce inter-subject...

Details Use of peptide-drug conjugation to reduce inter-subject... Use of peptide-drug conjugation to reduce inter-subject...

C - Chemistry, Metallurgy

12

Q

C12Q 1/00 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) C12Q 1/37 (2006.01)

Patent

CA 2477038

The present invention provides compositions and methods to decrease inter- patient variability particularly with respect to the systemic concentration of a drug. More particularly the invention relates to oral drugs which are conjugated to peptides or related carriers which alter release characteristics as compared to the analogous free drug. Figure (1) illustrates a typical release profile for reference drug v. a peptide conjugate drug of the present invention.

L'invention concerne des compositions et des procédés permettant de diminuer la variabilité entre des patients, plus spécifiquement par rapport à la concentration systémique d'un médicament. Plus spécifiquement, l'invention concerne des médicaments administrés par voie orale conjugués à des peptides ou des excipients associés qui modifient les caractéristiques de libération en comparaison du médicament libre analogue.

Affiliated with

Also associated with

Rating

Use of peptide-drug conjugation to reduce inter-subject... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of peptide-drug conjugation to reduce inter-subject..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of peptide-drug conjugation to reduce inter-subject... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1634701