Use of perfluoroalkyl-containing metal complexes as contrast...

Details Use of perfluoroalkyl-containing metal complexes as contrast... Use of perfluoroalkyl-containing metal complexes as contrast...

A - Human Necessities

61

K

A61K 49/00 (2006.01) A61K 49/08 (2006.01) A61K 49/10 (2006.01)

Patent

CA 2419223

The invention relates to the use of metal complexes containing perfluoroalkyl, comprising a critical micelle formation concentration < 10 -3 mol/1, a hydrodynamic micelle dynameter of (2 Rh) > 1 nm and a proton relaxivity in plasma (R1) > 101/mmol.s, as contrast agents in MR imaging for the representation of plaque, lymph node, infarcted and necrotic tissue and for independent representation of necrotic tissue and tumoural tissue.

La présente invention concerne l'utilisation de complexes métalliques contenant du perfluoroalkyle, présentant une concentration critique de formation de micelle < 10<-3> mol/l, un diamètre de micelle hydrodynamique (2 Rh) > 1 nm et une relaxivité de proton dans le plasma (R<1>) > 10 l/mmol.s, en tant qu'agents de contraste dans le cadre de l'imagerie RM à la fois pour la représentation de plaques, de ganglions lymphatiques, de tissus sujets à l'infarctus ou à la nécrose, et pour la représentation indépendante de tissus nécrosés et de tissus tumoraux.

Affiliated with

Also associated with

Rating

Use of perfluoroalkyl-containing metal complexes as contrast... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of perfluoroalkyl-containing metal complexes as contrast..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of perfluoroalkyl-containing metal complexes as contrast... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2004416