Use of phenyloxyaniline derivatives for imaging...

A - Human Necessities – 61 – K

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A61K 51/04 (2006.01)

Patent

CA 2687729

The present invention relates to the use of a specific compound, as described in detail below, having a high affinity to the peripheral benzodiazepine receptor for imaging cardiac and cardiovascular diseases for which inflammation and/or mitochondrial dysfunction and any other pathophysiological process leading to PBR activation are major contributing factor.

La présente invention porte sur l'utilisation d'un composé particulier, tel que décrit plus en détail ci-après, ayant une affinité élevée pour le récepteur de benzodiazépine périphérique pour l'imagerie de maladies cardiaques et cardiovasculaires pour lesquelles une inflammation et/ou un dysfonctionnement mitochondrial et tout autre procédé pathophysiologique conduisant à l'activation de PBR sont des facteurs de contribution majeurs.

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