A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/52 (2006.01) A61K 31/425 (2006.01) C12Q 1/02 (2006.01)
Patent
CA 2174082
The present invention relates to the use of a phosphatase inhibitor to activate transmembrane conductance regulator channels in channel-related diseases and/or chloride secretion insufficiencies. A typical channel-related disease is cystic fibrosis. It also relates to a pharmaceutical composition for the treatment of channel-related diseases and/or chloride secretion insufficiencies, which comprises at least one phosphatase inhibitor selected from the group consisting of isobutylmethylxanthine, theophylline, enprofylline, imidazothiazole pharmaceutical compounds, levamisole, bromotetramisole, R8231 bromotetramisole analog and pharmaceutical derivatives thereof in association with a pharmaceutically acceptable carrier.
La présente invention se rapporte à l'utilisation d'un inhibiteur de phosphatase pour activer les canaux régulateurs de conductance transmembranaire dans le cas de maladies associées aux canaux cellaires et/ou d'insuffisances de sécrétion de chlorure. Une maladie type associée aux canaux cellulaires est la fibrose kystique. L'invention se rapporte également à une composition pharmaceutique destinée au traitement de maladies associées aux canaux cellulaires et/ou d'insuffisances de sécrétion de chlorure, laquelle comprend au moins un inhibiteur de phosphatase choisi dans le groupe composé d'isobutylméthylxanthine, de théophylline, d'enprofylline, de composés pharmaceutiques à base d'imidazothiazole, de lévamisole, de tromotétramisole, d'analogues de tromotétramisole R8231 et de leurs dérivés pharmaceutiques, en association avec un excipient pharmaceutiquement acceptable.
Becq Frederic
Hanrahan John William
Swabey Ogilvy Renault
University Mcgill
LandOfFree
Use of phosphatase inhibitors for the manufacture of a... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Use of phosphatase inhibitors for the manufacture of a..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of phosphatase inhibitors for the manufacture of a... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1354729