A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 31/513 (2006.01) A61K 31/519 (2006.01) A61K 33/24 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2715353
The invention provides a method of treatment of metastatic colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with cetuximab, 5-FU, and leucovorin in a variety of treatment regimens. The invention also provides a use of picoplatin in conjunction with cetuximab, 5-FU, and leucovorin for treatment of metastatic colorectal cancer. The invention further provides kits adapted for administration of picoplatin in conjunction with cetuximab. Also, methods for determining dosage regimens for patients afflicted with a cancer comprising EGFR are provided.
L'invention concerne une méthode de traitement du cancer colorectal métastatique par administration du médicament anticancéreux à base de platine désigné sous le nom de picoplatine conjointement au cetuximab, au 5-FU, et à la leucovorine dans divers régimes thérapeutiques. L'invention concerne également l'utilisation de la picoplatine conjointement au cetuximab, au 5-FU, et à la leucovorine dans le traitement du cancer colorectal métastatique. L'invention concerne également des kits adaptés pour l'administration de picoplatine conjointement au cetuximab. L'invention concerne en outre des méthodes de détermination de dosages thérapeutiques pour des patients souffrant d'un cancer comprenant EGFR.
Karlin David A.
Martell Ronald A.
Poniard Pharmaceuticals Inc.
Ridout & Maybee Llp
LandOfFree
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