Use of pigmented retinal epithelial cells for creation of an...

Details Use of pigmented retinal epithelial cells for creation of an... Use of pigmented retinal epithelial cells for creation of an...

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 35/44 (2006.01) A61K 35/12 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2317115

The present invention relates to a novel in vivo method for creation of a localized immunosuppressive environment in tissue. The method involves the transplanting of pigmented retinal epithelial cells into a mammal thereby producing a localized immunosuppressive environment. The transplanted pigmented retinal epithelial cells may also be used to produce therapeutic proteins or other biologically active molecules that may be useful in treatment of diseases.

L'invention concerne un nouveau procédé in vivo permettant de créer dans les tissus un environnement immunosuppresseur localisé. Ce procédé consiste à transplanter des cellules épithéliales rétiniennes pigmentées dans un mammifère de manière à produire un environnement immunosuppresseur localisé. Les cellules épithéliales rétiniennes pigmentées peuvent également être utilisées pour produire des protéines thérapeutiques ou d'autres molécules biologiquement actives pouvant être utiles dans le traitement de maladies.

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