Use of platelet activating factor antagonists as...

A - Human Necessities – 61 – K

Patent

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A61K 31/55 (2006.01) A61K 31/365 (2006.01) A61K 31/44 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2083611

2083611 9118608 PCTABS00008 This invention relates to a method for treating pruritus by administering a therapeutically effective amount of a PAF antagonist to a mammal afflicted with pruritus. The PAF antagonists may, for example, be selected from synthetic PAF analogues, natural products isolated from plants having PAF antagonist activity, and triazolobenzodiazepines. The PAF antagonists are preferably applied topically to the afflicted site but systemic such as oral, parenteral, nasal and intrarectal administration, is also possible.

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