Use of polyamine antagonists for the treatment of glaucoma

Details Use of polyamine antagonists for the treatment of glaucoma Use of polyamine antagonists for the treatment of glaucoma

A - Human Necessities

61

K

A61K 31/445 (2006.01) A61K 31/00 (2006.01)

Patent

CA 2194504

Polyamine antagonists are found to be effective in preventing or reducing visual field loss associated with glaucoma. Especially preferred are certain 1- phenyl-2-piperidinoalkanol derivatives, such as eliprodil and ifenprodil.

On constate que des antagonistes de polyamines préviennent ou limitent efficacement le rétrécissement du champ visuel dû au glaucome. On préfère notamment utiliser certains dérivés de 1-phényle-2-pipéridinoalcanol tels que l'éliprodile et l'ifenprodile.

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