Use of polyunsaturated ketones for the treatment of psoriasis

Details Use of polyunsaturated ketones for the treatment of psoriasis Use of polyunsaturated ketones for the treatment of psoriasis

A - Human Necessities

61

K

A61K 31/557 (2006.01) A61K 31/121 (2006.01) A61P 17/06 (2006.01)

Patent

CA 2473687

Psoriasis is a common, chronic, inflammatory skin disorder. This invention provides the use of a compound of formula (I) R-CO-X (Wherein R is a C16-24 unsaturated hydrocarbon group optionally interrupted .alpha., .beta., .gamma., or .delta. to the carbonyl group by a heteroatom or group of heteroatoms selected from S, O, N, SO, SO2 said hydrocarbon group comprising at least 5 non-conjugated double bonds; and X is an electron withdrawing group) in the manufacture of a medicament for the treatment of psoriasis.

Le psoriasis est une maladie commune, chronique et inflammatoire de la peau. L'invention concerne l'utilisation d'un composé représenté par la formule (I): R-CO-X dans laquelle R représente un groupe hydrocarbure insaturé C¿16-24? éventuellement .alpha., .beta., .gamma., ou .delta. interrompu par rapport au groupe carbonyle par un hétéroatome ou un groupe d'hétéroatomes sélectionné dans S, O, N, SO, SO¿2?, ledit groupe hydrocarbure comprenant au moins 5 doubles liaisons non conjuguées ; X représente un groupe de retrait d'électrons, afin de préparer un médicament servant à traiter le psoriasis.

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