C - Chemistry – Metallurgy – 08 – J
Patent
C - Chemistry, Metallurgy
08
J
183/19, 252/31
C08J 3/14 (2006.01) B01J 20/26 (2006.01) A61K 7/00 (1990.01) G01N 30/48 (1990.01)
Patent
CA 1325203
Abstract of the Disclosure A filler for use in chromatography comprises porous spherical grains of poly(.alpha.-amino acid). The spherical grains can be produced by a method which comprises the steps of preparing a solution of hydrophobic poly(.alpha.-amino acid) such as poly n-leucine dissolved in an organic solvent containing an additive; adding the solution to an aqueous medium and agitating the medium so as to obtain a dispersion of the spherical grains of the poly(.alpha.-amino acid) dispersed in the aqueous medium while evaporating the organic solvent; taking out the spherical grains of polyamino acid from the disper- sion and removing the additive from the grains. The additive is noncompatible with the organic solvent in which the poly (.alpha.-amino acid) is dissolved, and has a higher boiling point than those of the organic solvent and the aqueous medium.
615968
Hirayama Chuichi
Ihara Hirotaka
Motozato Yoshiaki
Hirayama Chuichi
Ihara Hirotaka
Juridical Foundation The Chemo-Sero-Therapeutic Research Institu
Motozato Yoshiaki
Ogilvy Renault
LandOfFree
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