Use of posaconazole for the treatment of fungal infections

Details Use of posaconazole for the treatment of fungal infections Use of posaconazole for the treatment of fungal infections

A - Human Necessities

61

K

A61K 31/4196 (2006.01) A61K 31/4178 (2006.01) A61K 31/496 (2006.01) A61P 31/10 (2006.01) C07D 249/00 (2006.01)

Patent

CA 2499897

The use of posaconazole for the preparation of a medicament for the treatment or prevention of fungal infections in humans of 12 years and older in need of such treatment or prevention the medicament which comprises an effective amount of posaconazole in divided doses two to four times a day to produce an arithmetic mean steady state average maximum plasma concentration of posaconazole of at least about 300 ng/mL to at least about 550 ng/mL is disclosed.

L'invention concerne l'utilisation de posaconazole pour la préparation d'un médicament destiné au traitement ou à la prévention d'infections fongiques chez des humains de 12 années et plus nécessitant un tel traitement ou prévention, ce médicament comprenant une quantité effective de posaconazole en doses divisées, correspondant à des prises de deux à quatre doses par jour, afin de produire une concentration plasmatique moyenne d'état stationnaire avec une moyenne arithmétique de posaconazole d'au moins 300 ng/ml environ jusqu'à 550 ng/ml environ.

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