Use of pp2a phosphatase modulators in the treatment of...

Details Use of pp2a phosphatase modulators in the treatment of... Use of pp2a phosphatase modulators in the treatment of...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 38/46 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) A61P 25/18 (2006.01) A61P 25/24 (2006.01) C07K 14/705 (2006.01) G01N 33/50 (2006.01) G01N 33/573 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2489024

The invention relates to the use of PP2A/B.gamma. and to the use of a PP2A phosphatase comprising the PP2A/B.gamma. subunit for screening for modulators thereof. The use of these modulators for treating mental disorders such as bipolar disorder, schizophrenia and depression, and drugs comprising these modulators are further disclosed. The invention also discloses biallelic markers located in the gene encoding PP2A/B.gamma. and their use for diagnosing mental disorders.

L'invention porte sur l'utilisation de PP2A/B.gamma., et sur l'utilisation d'une phosphatase PP2A comprenant la sous-unité PP2A/B.gamma. dans un procédé de criblage destiné à identifier des modulateurs de celle-ci. L'invention concerne également l'utilisation de ces modulateurs pour le traitement de troubles mentaux tels que les troubles bipolaires, la schizophrénie et la dépression, ainsi que des médicaments comprenant ces modulateurs. L'invention concerne en outre des marqueurs bialléliques localisés dans le gène codant pour PP2A/B.gamma., et l'utilisation de ces marqueurs pour le diagnostic de troubles mentaux.

Affiliated with

Also associated with

Rating

Use of pp2a phosphatase modulators in the treatment of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of pp2a phosphatase modulators in the treatment of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of pp2a phosphatase modulators in the treatment of... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1576355