Use of prenyltransferase inhibitors for preparing a medicine...

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A61K 31/425 (2006.01) A61K 31/215 (2006.01) A61K 31/42 (2006.01) A61K 31/445 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/55 (2006.01) A61K 31/66 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2337261

The invention concerns the use of prenyltransferase inhibitors for preparing a medicine for treating pathologies resulting from prenylation of the .gamma. subunit of G protein. Said diseases comprise in particular diseases related to the following biological functions or disorders: smell, taste, light perception, neurotransmission, neurodegeneration, endocrine and exocrine gland functioning, autocrine and paracrine regulation, blood pressure, embryogenesis, viral infection, immunological functions, diabetes and obesity.

L'invention concerne l'utilisation d'inhibiteurs de prényltransférases pour préparer un médicament destiné à traiter les pathologies qui résultent de la prénylation de la sous-unité .gamma. de la protéine G. Ces maladies comprennent en particulier des maladies liées aux fonctions biologiques ou désordres suivants: odorat, goût, perception de la lumière, neurotransmission, neurodégénérescence, fonctionnement des glandes endocrines et exocrines, régulation autocrine et paracrine, tension artérielle, embryogénèse, infection virale, fonctions immunologiques, diabète et obésité.

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