Use of protease inhibitors for treating skin wounds

Details Use of protease inhibitors for treating skin wounds Use of protease inhibitors for treating skin wounds

A - Human Necessities

61

K

A61K 38/57 (2006.01) A61K 38/06 (2006.01)

Patent

CA 2326438

The healing of chronic wounds, such as leg ulcers, is accelerated via topical administration of a serine protease inhibitor, such as PAI-2. Wound healing also is promoted using combinations of protease inhibitors, such as PAI-2 with other serine protease inhibitors and/or with protease inhibitors such as inhibitors of metalloproteinases, acid proteases, and thiol proteases, respectively.

On accélère la cicatrisation de blessures chroniques, telles que les ulcères de jambe, au moyen de l'administration topique d'un inhibiteur de la sérine protéase, tel que PAI-2. On accélère également la cicatrisation de blessures en utilisant une combinaison d'inhibiteurs de la sérine protéase, tels que PAI-2, avec d'autres inhibiteurs de la sérine protéase et/ou avec des inhibiteurs de la protéase, tels que des inhibiteurs de la métalloprotéase, de la protéase acide et de la protéase thiol.

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