Use of protein histidine phosphatase

Details Use of protein histidine phosphatase Use of protein histidine phosphatase

C - Chemistry, Metallurgy

12

N

C12N 9/16 (2006.01) C12N 9/88 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2439934

The invention relates to the use of polypeptides with protein histidine phosphatase activity derived from mammalians, antibodies directed against them and DNA or RNA sequences complementary to mRNA sequences encoding polypeptides with protein histidine phosphatase activity for the modulation of ATP-citrate lyase and treatment of correlated pathophysiologic functions.

L'invention a trait à l'utilisation de polypeptides présentant une activité de protéine histidine phosphatase, dérivés de mammifères, à des anticorps dirigés contre ces polypeptides, ainsi qu'à des séquences ADN ou ARN complémentaires de séquences ARNm codant les polypeptides à activité de protéine histidine phosphatase pour la modulation de l'ATP-citrate lyase et le traitement de fonctions pathophysiologiques corrélées.

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