Use of prothymosin in the diagnosis and treatment of...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2299436

Prothymosin expression is up-regulated in endometriotic tissue. This invention provides methods of diagnosing endometriosis by detecting up-regulation of a prothymosin gene product, and methods of treating endometriosis by down- regulating expression of prothymosin in ectopic or eutopic endometriotic tissue.

Selon cette invention, on régule positivement l'expression de la prothymosine dans un tissu endométrial. L'invention concerne des procédés de diagnostic de l'endométriose par la détection de régulation positive d'un produit génique de prothymosine ainsi que des procédés pour traiter l'endométriose par la régulation négative de l'expression de prothymosine dans un tissu endométrial ectopique ou eutopique.

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