Use of pyrene to carry peptides across the blood brain barrier

Details Use of pyrene to carry peptides across the blood brain barrier Use of pyrene to carry peptides across the blood brain barrier

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2718860

Described are methods for delivering a peptide agent across the blood-brain barrier, comprising administering to a subject a conjugate comprising (i) a peptide agent and pyrene, and related detection and therapeutic methods.

Linvention concerne des procédés permettant ladministration dun agent peptidique à travers la barrière hémato-encéphalique, qui comprennent ladministration à un sujet dun conjugué comportant (i) un agent peptidique et du pyrène, et les procédés thérapeutiques et de détection associés.

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