Use of quinic, shikimic acids and their derivatives for...

Details Use of quinic, shikimic acids and their derivatives for... Use of quinic, shikimic acids and their derivatives for...

C - Chemistry, Metallurgy

07

K

C07K 14/00 (2006.01) A61K 31/19 (2006.01) A61K 38/04 (2006.01) A61K 38/16 (2006.01) C07K 5/02 (2006.01) C07K 5/023 (2006.01) C07K 5/037 (2006.01) C07K 7/02 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2388663

The invention concerns the use of quinic, shimic acids and their derivatives for preparing mannose receptor ligands, the resulting ligands and the uses of said ligands, in particular for preparing medicines and, more particularly for preparing vaccines and medicines for vectoring an active principle to target cells expressing the mannose receptor or a receptor related thereto, for transfecting DNA and RNA sequences and numerous other uses in gene therapy, and for preparing laboratory reagents, in particular diagnostic reagents.

La présente invention se rapporte à l'utilisation des acides quinique, shikimique et de leurs dérivés pour la préparation de ligands du récepteur du mannose, aux ligands ainsi préparés, ainsi qu'aux applications de ces ligands, notamment pour la préparation de médicaments et, plus particulièrement pour la préparation de vaccins et de médicaments destinés à assurer la vectorisation d'un principe actif vers des cellules cibles exprimant le récepteur du mannose ou un récepteur lui étant apparenté, la transfection de séquences d'ADN et d'ARN et ses multiples utilisations en thérapie génique, et la préparation de réactifs de laboratoire, notamment de réactifs de diagnostic.

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