Use of quinone and hydroquinone derivatives for the teatment...

A - Human Necessities – 61 – K

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A61K 31/12 (2006.01) A61K 31/122 (2006.01) A61K 31/38 (2006.01) A61K 31/381 (2006.01) A61K 31/415 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01) A61K 31/4406 (2006.01)

Patent

CA 2196426

A pharmaceutical composition for treating cachexia which contains a compound (I), wherein R1, R2 is H, alkyl, alkoxy, may form -CH=CH-CH=CH-; R3 is H, alkyl; R4 is N-containing heterocyclic; R5 is H, alkyl, hydroxyalkyl, carboxyl; Z is (a), -CH=CH-, (b) or (c); (R0 is H, alkyl); n is 0-12; m is 0- 3; k is 0-7, or a salt thereof.

Une composition pharmaceutique, destinée à traiter la cachexie, contient un composé de formule (I), ou son sel, où R?1¿ et R?2¿ représentent H, alkyle, alcoxy, ou bien peuvent former -CH=CH-CH=CH-; R?3¿ représente H ou alkyle; R?4¿ représente un groupe hétérocyclique contenant N; R?5¿ représente H, alkyle, hydroxyalkyle ou carboxyle; et Z représente (a), -CH=CH-, (b) ou (c) (où R?0¿ représente H ou alkyle); n vaut de 0 à 12; m vaut de 0 à 3; k vaut de 0 à 7.

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