A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/00 (2006.01) A61K 31/165 (2006.01) A61K 31/401 (2006.01) A61K 31/41 (2006.01) A61K 31/451 (2006.01) A61K 31/55 (2006.01) A61P 9/00 (2006.01)
Patent
CA 2580862
The present invention provides the use of a therapeutically effective amount of a renin inhibitor, or pharmaceutically acceptable salt thereof, alone or in combination with (i) an ACE inhibitor or a pharmaceutically acceptable salt thereof; or (II) an angiotensin II receptor blocker or a pharmaceutically acceptable salt thereof, for the manufacture of a medicament for the prevention of, delay progression to overt to, or the treatment of diastolic dysfunction or diastolic heart failure in a warm-blooded animal.
L'invention concerne l'utilisation d'une quantité efficace sur le plan thérapeutique d'un inhibiteur de rénine ou d'un de ses sels acceptables sur le plan pharmaceutique, seul ou combiné à: (i) un inhibiteur de ACE ou un de ses sels acceptables sur le plan pharmaceutique ou (ii) un bloqueur du récepteur d'angiotensine II ou un de ses sels acceptables sur le plan pharmaceutique, afin de préparer un médicament servant à prévenir, à limiter la progression ou à traiter le dysfonctionnement diastolique ou une cardiopathie diastolique chez un animal à sang chaud.
Feldman David Louis
Luft Friedrich Cameron
Mueller Dominik Nicolas
Webb Randy Lee
Fetherstonhaugh & Co.
Novartis Ag
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