C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/02 (2006.01) A61K 31/728 (2006.01) A61K 35/34 (2006.01)
Patent
CA 2513337
The present the invention relates to a new use of retinoic esters of hyaluronic acid, that exhibit pro-differentiating activity on totipotent stem cells. The invention also relates to a process to differentiate said stem cells and to select molecules capable of modulating the pro-differentiating activity of these esters.
L'invention concerne une nouvelle utilisation d'esters rétinoïques d'acide hyaluronique qui activent la différenciation de cellules souches totipotentes. L'invention concerne aussi un procédé permettant de mettre en oeuvre une différenciation de telles cellules souches et de sélectionner des molécules pouvant moduler l'action d'activation de ces esters.
Maioli Margherita
Perbellini Alberto
Ventura Carlo
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sintofarm S.p.a.
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