Use of riboflavin in the treatment of hypertension

Details Use of riboflavin in the treatment of hypertension Use of riboflavin in the treatment of hypertension

A - Human Necessities

61

K

A61K 31/525 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2679217

The invention provides the use of riboflavin in the manufacture of a medicament for the treatment or prophylaxis of elevated blood pressure in a subject homozygous or heterozygous for the MTHFR C677T polymorphism. The invention also provides a pharmaceutical product for the treatment or prophylaxis of elevated blood pressure in a subject homozygous or heterozygous for the MTHFR C677T polymorphism, comprising a pharmaceutically effective amount of an anti-hypertensive agent and riboflavin, and the invention further provides a method of treatment of such a subject comprising the administration of riboflavin.

L'invention porte sur l'utilisation de riboflavine dans la fabrication d'un médicament pour le traitement ou la prophylaxie de l'hypertension chez un sujet homozygote ou hétérozygote pour le polymorphisme MTHFR C677T. L'invention porte également sur un produit pharmaceutique pour le traitement ou la prophylaxie de l'hypertension chez un sujet homozygote ou hétérozygote pour le polymorphisme MTHFR C677T, comprenant une quantité pharmaceutiquement efficace d'un agent hypotenseur et de riboflavine. L'invention porte en outre sur one méthode de traitement d'un tel sujet par administration de riboflavine.

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