Use of ribose-cysteine to treat hypoxia by enhancing...

A - Human Necessities – 61 – K

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A61K 31/426 (2006.01) A61P 9/10 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2587616

A therapeutic method is provided comprising treating a mammal subject to hypoxia with an amount of 2(R,S)-D-ribo-(1',2',3',4'- tetrahydroxybutyl)thiazolidine-4(R)-carboxylic acid (RibCys) or a pharmaceutically acceptable salt thereof effective to both maintain, restore or increase both the ATP levels and the glutathione (GSH) levels in said tissue.

Cette invention concerne une méthode thérapeutique consistant à traiter un mammifère sujet à l'hypoxie au moyen d'une dose efficace d'acide 2(R,S)-D-ribo-(1',2',3',4';-tétrahydroxybutyl)thiazolidine-4(R)-carboxylique (RibCys) ou un sel pharmaceutiquement acceptable de ce composé pour à la fois maintenir, rétablir ou augmenter et les niveaux d'ATP, et les niveaux de glutathione (GSH) dans lesdits tissus.

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