Use of rnai inhibiting parp activity for the manufacture of...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/11 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2533423

The present invention relates to the use of an agent that inhibits the activity of an enzyme that mediates repair of a DNA strand break in the manufacture of a medicament for the treatment of diseases caused by a defect in a gene that mediates homologous recombination.

La présente invention a trait à l'utilisation d'un agent inhibiteur de l'activité d'une enzyme intervenant dans la réparation de la rupture d'un brin d'ADN dans la fabrication d'un médicament pour le traitement de maladies provoquées par un défaut dans un gène entraînant la recombinaison homologue.

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