Use of runx3 and mir-532-5p as cancer markers and...

Details Use of runx3 and mir-532-5p as cancer markers and... Use of runx3 and mir-532-5p as cancer markers and...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 31/7105 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2727195

The invention relates to methods for cancer diagnosis, prognosis, and treatment based on the expression or activity levels of RUNX3 and miR- 532-5p. Also disclosed is a method of reducing the inhibition of RUNX3 by miR-532-5p with an agent that interferes with the interaction between RUNX3 and miR-532-5p transcripts.

La présente invention concerne des procédés de diagnostic, pronostic et traitement du cancer basés sur l'expression ou les niveaux d'activité de RUNX3 et de miR-532-5p. Elle concerne également un procédé permettant de réduire l'inhibition de RUNX3 par miR-532-5p à l'aide d'un agent qui interfère avec l'interaction entre des transcriptions de RUNX3 et de miR-532-5p.

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