Use of russell's viper venom-induced plasma factor xa...

Details Use of russell's viper venom-induced plasma factor xa... Use of russell's viper venom-induced plasma factor xa...

C - Chemistry, Metallurgy

12

Q

C12Q 1/56 (2006.01) G01N 33/86 (2006.01)

Patent

CA 2389747

The invention relates to a method of monitoring the effect of a direct of indirect Factor Xa inhibitors comprising the steps of collecting a plasma sample from a patient, adding a solution of Russell's viper venom to the plasma sample and measuring the clotting time or the residual FXa activity chromogenically.

L'invention concerne un procédé de contrôle de l'effet des inhibiteurs Facteur Xa indirects comportant les étapes de collection d'un échantillon de plasma d'un patient, l'adjonction d'une solution de venin de vipère de Russell audit échantillon de plasma et enfin la mesure du temps de coagulation ou l'activité Facteur Xa résiduelle, de manière chromogène.

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