Use of s-ydcb and b-ydcb, essential bacterial genes

Details Use of s-ydcb and b-ydcb, essential bacterial genes Use of s-ydcb and b-ydcb, essential bacterial genes

C - Chemistry, Metallurgy

12

Q

C12Q 1/18 (2006.01) C07K 14/315 (2006.01) C07K 14/32 (2006.01) G01N 33/94 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2343965

Disclosed are methods for using the essential genes and polypeptides "S-ydcB", found in Streptococcus pneumoniae, and "B-ydcB", found in Bacillus subtilis. These genes and polypeptides, as well as homologs and orthologs thereof, can be used to identify antibacterial agents for treating a broad spectrum of bacterial infections.

L'invention concerne des procédés d'utilisation des polypeptides et des gènes essentiels <= S-ydcB >= qu'on trouve dans Streptococcus pneumoniae, et <= B-ydcB >= qu'on trouve dans Bacillus subtilis. On peut utiliser ces gènes et ces polypeptides, ainsi que leurs homologues et orthologues, afin d'identifier des agents antibactériens servant à traiter un large spectre d'infections bactériennes.

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