Use of secretin-receptor ligands in treatment of cystic...

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 38/22 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2412839

The invention is based on the finding that the secretin receptor is expressed in tissues present in the distal lung of humans. In patient with CF, levels of the receptor are elevated compared to normal tissue. Treatment of tissue by secretin stimulates the movement of negative ions in the tissue. The invention provides methods of treatment of cystic fibrosis or COPD in a patient by administering to said patient an effective amount of an agent which triggers anion efflux in respiratory tissue via the activation of a secretin receptor.

L'invention concerne la découverte du fait que le récepteur de la sécrétine s'exprime dans des tissus présents dans le poumon distal d'êtres humains. Chez un patient atteint de fibrose cystique, les niveaux du récepteur sont élevés comparés à ceux d'un tissu normal. Le traitement du tissu par la sécrétine stimule le mouvement des ions négatifs dans le tissu. L'invention concerne également des procédés de traitement de la fibrose cystique ou de la bronchopneumopathie chronique obstructive (COPD) chez un patient, grâce à l'administration, audit patient, d'une quantité efficace d'un agent qui déclenche un flux d'anions dans le tissu respiratoire par l'activation d'un récepteur de sécrétine.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Use of secretin-receptor ligands in treatment of cystic... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of secretin-receptor ligands in treatment of cystic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of secretin-receptor ligands in treatment of cystic... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1398189

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.