Use of selected compounds for protection of neurones and...

A - Human Necessities – 61 – K

Patent

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A61K 31/475 (2006.01) A61K 31/4535 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2592543

Certain compounds, including 5,6-dihydro-3,9-dihydroxyindolo[2,1-a- isoquinolin12yl)[4-[2~-(1-piperidinyl) ethoxy]phenyl]- methanone and arzoxifen, are useful for providing protection to oligodendrocytes and neurons of multiple sclerosis patients.

L'invention concerne certains composés, notamment 5,6-dihydro-3,9-dihydroxyindolo[2,1-a-isoquinoline12yl)[4-[2--(1-pipéridinyl) éthoxy]phényl]- méthanone et arzoxifène, que l'on utilise pour protéger des oligodendrocytes et des neurones de patients souffrant de la sclérose en plaques.

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