A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/55 (2006.01)
Patent
CA 2605918
The invention relates to methods of and treatments for using pharmaceutical compositions from a class of compounds that directly or indirectly selectively modulates GABAA chloride channel activity to treat alcohol and/or stimulant substance abuse. The present invention also relates to methods of, and protocols for, relieving symptoms associated with alcohol and/or stimulant substance abuse in a comprehensive treatment plan. More specifically, the present invention relates to the use of a selective chloride channel modulator, such as flumazenil, to treat alcohol and/or psychostimulant dependency, the withdrawal symptoms associated therewith, and the cravings associated therewith.
L'invention concerne des procédés d'utilisation de compositions pharmaceutiques, et des traitements faisant appel à des compositions pharmaceutiques, d'une classe de composés qui modulent de manière sélective, directement ou indirectement, l'activité du canal chlorure GABAA dans le traitement de l'alcoolisme et/ou de l'utilisation abusive de substances stimulantes. L'invention concerne également des procédés, et les protocoles associés, qui permettent de soulager les symptômes associés à l'alcoolisme et/ou à l'utilisation abusive de substances stimulantes selon un plan de traitement complet. En particulier, l'invention concerne l'utilisation d'un modulateur sélectif du canal chlorure, tel que le flumazénil, dans le traitement de l'alcoolisme et/ou de la dépendance aux psychostimulants, et des symptômes de sevrage et de l'état de manque qui leur sont associés.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Hythiam Inc.
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