Use of self-incompatibility receptor proteins (slg and srk)...

Details Use of self-incompatibility receptor proteins (slg and srk)... Use of self-incompatibility receptor proteins (slg and srk)...

A - Human Necessities

61

K

A61K 38/16 (2006.01) C07K 14/415 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2139552

The self-incompatibility receptor proteins (SLG and SRK) plants are useful in the treatment of allergic diseases by IgE. Likewise, they are useful to manufacture drugs used for said treatments. The proteins can come from any plant, among which Brassica, Alnus glutinosa (alder), Parietaria judaica (pellitory), Populus alba (poplar), for example, can be cited. Said proteins can totally or partially inhibit the IgE-allergen bond when tested "in vitro" in numerous systems, among which the mite of home dust, bee poison and pollen of Phleum pratense, Parietaria judaica, grass and Olea europea can be cited. Therefore, they are products useful in the treatment of allergic diseases.

Les récepteurs protéiques auto-incompatibles (SLG et SRK) extraits de plantes se révèlent utiles dans le traitement, au moyen de l'IgE, des maladies causées par des réactions allergiques. Ils sont également utiles dans la synthèse de médicaments utilisés dans ces traitements. Les protéines peuvent provenir de n'importe quelle plante, et en particulier des Brassica, des Alnus glutinosa (aulnes), des Parietaria judaica (pariétaires) ou des Populus alba (peupliers). Ces protéines peuvent empêcher totalement ou partiellement l'allergène IgE de former un lien, comme l'ont démontré des tests effectués in vitro dans de nombreux systèmes, par exemple, la mite domestique, le venin d'abeille et le pollen des Phleum pratense, Parietaria judaica, l'herbe ou l'Olea europea. Il s'agit donc de produits utiles dans le traitement des affections allergiques.

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