Use of sip1 as determinant of breast cancer stemness

Details Use of sip1 as determinant of breast cancer stemness Use of sip1 as determinant of breast cancer stemness

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2716623

The present invention relates to the diagnosis and treatment of cancer. More specifically, it relates to the use of SIP 1 nucleic acid and/or protein for the detection of breast cancer stem cells, and the repression of the gene and/or the inactivation of the protein to repress the differentiation of cells into cancer cells and to inhibit metastasis of breast cancer tumors.

La présente invention concerne le diagnostic et le traitement du cancer. Plus particulièrement, elle concerne lutilisation de lacide nucléique et/ou de la protéine SIP1 pour la détection de cellules souches dans le cancer du sein, et la répression du gène et/ou linactivation de la protéine pour réprimer la différenciation de cellules dans les cellules cancéreuses et inhiber les métastases des tumeurs du cancer du sein.

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