Use of sirna to achieve down regulation of an endogenous...

Details Use of sirna to achieve down regulation of an endogenous... Use of sirna to achieve down regulation of an endogenous...

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 48/00 (2006.01) C07H 21/02 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2717637

The present invention relates to the combinatorial use of an siRNA targeted against an endogenous gene to knock out or knock down expression of the endogenous gene in a host and a delivery of a polynucleotide encoding the gene in a delivery vehicle/expression vector to the host to provide expression in the host of the protein encoded by the polynucleotide.

La présente invention porte sur l'utilisation combinatoire d'un ARNsi, ciblé contre un gène endogène pour inactiver ou réduire l'expression du gène endogène chez un hôte, et de l'administration d'un polynucléotide codant pour le gène dans un véhicule d'administration/vecteur d'expression à l'hôte afin dobtenir l'expression chez l'hôte de la protéine codée par le polynucléotide.

Affiliated with

Also associated with

Rating

Use of sirna to achieve down regulation of an endogenous... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of sirna to achieve down regulation of an endogenous..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of sirna to achieve down regulation of an endogenous... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1929409