Use of snps for the diagnosis of a pain protective haplotype...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2662721

The present invention relates to an in vitro method for diagnosing a genetic predisposition or susceptibility for pain in a mammal which comprises detecting of at least one particular single nucleotide polymorphism (SNP) in a sample obtained from said mammal in the genomic locus-derived nucleic acid or fragment thereof of the locus GCH1.

La présente invention concerne une méthode in vitro de diagnostic d'une prédisposition ou susceptibilité génétique à la douleur chez un mammifère, consistant à détecter au moins un polymorphisme nucléotidique (SNP) particulier dans un échantillon obtenu dudit mammifère dans l'acide nucléique dérivé du locus génomique ou un fragment de celui-ci du locus GCH1.

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