Use of sodium/hydrogen exchange inhibitors from the...

A - Human Necessities – 61 – K

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A61K 31/185 (2006.01) A61K 31/165 (2006.01) A61K 31/255 (2006.01) A61K 31/403 (2006.01) A61K 31/404 (2006.01) A61K 31/417 (2006.01) A61K 31/435 (2006.01) A61K 31/4418 (2006.01) A61K 31/454 (2006.01) A61K 31/47 (2006.01) A61K 31/496 (2006.01) A61K 45/06 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2476446

Inhibitors of cellular sodium/hydrogen exchangers display an inhibiting effect on the secretion of von-Willebrand factor and/or increased expression of P- selektin. Said inhibitors can thus be used for the treatment of thrombotic and inflammatory diseases.

Des inhibiteurs de l'antiporteur ions sodium-hydrog­ne cellulaire ont un effet inhibiteur sur la s~cr~tion du facteur von Willebrand et/ou sur l'expression ~lev~e de la P-selectine. Ces inhibiteurs peuvent donc Útre utilis~s pour le traitement de maladies thrombotiques et inflammatoires.

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