Use of soluble fgl2 as an immunosuppressant

Details Use of soluble fgl2 as an immunosuppressant Use of soluble fgl2 as an immunosuppressant

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) A61K 38/19 (2006.01) A61K 38/48 (2006.01) A61P 37/06 (2006.01) C07K 14/52 (2006.01) C07K 14/745 (2006.01) C07K 14/75 (2006.01) C12N 9/64 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2477312

Methods and compositions for inducing immune suppression are disclosed. The methods involve administering an effective amount of a soluble fgl2 protein or a nucleic acid encoding a soluble fgl2 protein. The methods are useful in preventing graft rejection, autoimmune disease, and allergies.

L'invention concerne des méthodes et des compositions permettant d'induire l'immunosuppression. Les méthodes décrites dans cette invention consistent à administrer une quantité efficace d'une protéine fgl2 soluble ou d'un acide nucléique codant pour une protéine fgl2 soluble. Les méthodes décrites dans l'invention sont utiles pour prévenir un rejet de greffe, une maladie auto-immune et des allergies.

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