Use of solutions of atelocollagen and polyholosides, for...

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A61K 9/50 (2006.01) A23P 1/04 (2006.01) A61K 8/11 (2006.01) A61K 8/65 (2006.01) A61K 8/67 (2006.01) A61K 8/73 (2006.01) A61K 9/16 (2006.01) A61Q 19/00 (2006.01) B01J 13/02 (2006.01) B01J 13/04 (2006.01) B01J 13/10 (2006.01)

Patent

CA 2009065

The invention relates to microcapsules with a mixed wall of crosslinked atelocollagen and polyholosides, for example glycosaminoglycans, and to processes for the manufacture of the said microcapsules. According to the invention, the microcapsules comprise a mixed wall of crosslinked atelocollagen and polyholosides, for example glycosaminoglycans, the proportion of polyholosides, for example glycosaminoglycans, relative to the atelocollagen preferably being between 18 and 50% by weight. These microcapsules can be manufactured either by a process involving interfacial cross-linking or by the extrusion of a laminar flow which is broken up by vibrations into individual droplets, which fall into a crosslinking bath. These microcapsules are biocompatible by virtue of the presence of atelocollagen, which has most of the advantageous properties of collagen, namely a very low antigenicity and a perfect biodegradability. They are therefore particularly suitable for the manufacture of cosmetic, pharmaceutical or food compositions.

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